黄文茂课题组

Ions shaping the mechanics of chromosomes in mitosis

1. Wenmao Huang, Zongqing Lim, Jie Yan. Ions shaping the mechanics of chromosomes in mitosis. Nat. Mater. 2024, 23, 1468–1470. 文章链接

DNA Mechanics: From Single Stranded to Self-Assembled

2. Linfeng Yang, Qian Li, Zhilei Ge, Chunhai Fan*, Wenmao Huang*. DNA Mechanics: From Single Stranded to Self-Assembled. Nano Lett. 2024, 24, 38, 11768-11778. 文章链接

1. Wenmao Huang, Zongqing Lim, Jie Yan. Ions shaping the mechanics of chromosomes in mitosis. Nat. Mater. 2024, 23, 1468–1470.

2. Linfeng Yang, Qian Li, Zhilei Ge, Chunhai Fan*, Wenmao Huang*. DNA Mechanics: From Single Stranded to Self-Assembled. Nano Lett. 2024, 24, 38, 11768-11778.

Before SJTU:

In situ single-molecule investigations of the impacts of biochemical perturbations on conformational intermediates of monomeric α-synuclein

1. Wenmao Huang*, Jingzhun Liu, Shimin Le, Mingxi Yao, Yi Shi, Jie Yan. In situ single-molecule investigations of the impacts of biochemical perturbations on conformational intermediates of monomeric α-synuclein. APL Bioengineering, 2024, 8 (1) (一作+共通，Featured Article) 文章链接

Unveiling Mechanical Activation: GAIN Domain Unfolding and Dissociation in Adhesion GPCRs

2. Chaoyu Fu^#, Wenmao Huang^#, Qingnan Tang, Minghui Niu, Shiwen Guo, Tobias Langenhan, Gaojie Song, Jie Yan. Unveiling Mechanical Activation: GAIN Domain Unfolding and Dissociation in Adhesion GPCRs. Nano Lett. 2023, 23, 20, 9179–9186. 文章链接

Mechanical stabilization of a bacterial adhesion complex

3. Wenmao Huang, Shimin Le, Yuze Sun, Dennis Jingxiong Lin, Mingxi Yao, Yi Shi, Jie Yan . Mechanical stabilization of a bacterial adhesion complex. J. Am. Chem. Soc., 2022, 144, 37, 16808-16818. 文章链接

Maleimide–thiol adducts stabilized through stretching

4. Wenmao Huang, Xin Wu, Xiang Gao, Yifei Yu, Hai Lei, Zhenshu Zhu, Yi Shi, Yulan Chen, Meng Qin, Wei Wang, Yi Cao. Maleimide–thiol adducts stabilized through stretching. Nat. Chem., 2019, 11, 310–319. 文章链接

Direct measurement of the hydrophobic free energy of a single polymer nanosphere

5. Weishuai Di^#, Xiang Gao^#, Wenmao Huang^#, Yang Sun, Hai Lei, Yang Liu, Wenfei Li, Yiran Li, Xin Wang, Meng Qin, Zhenshu Zhu, Yi Cao, Wei Wang. Direct measurement of length scale dependence of the hydrophobic free energy of a single collapsed polymer nanosphere. Phys. Rev. Lett., 2019, 122, 047801. 文章链接

Single Molecule Study of Force-Induced Rotation of Carbon–Carbon Double Bonds in Polymers

6. Wenmao Huang^#, Zhenshu Zhu^#, Jing Wen^#, Xin Wang, Meng Qin, Yi Cao, Haibo Ma, Wei Wang. Single Molecule Study of Force-Induced Rotation of Carbon–Carbon Double Bonds in Polymers. ACS Nano, 2017, 1, 194-203 (Highlighted by "Twist and Shout: Single-Molecule Mechanochemistry"). 文章链接

Lipid-dependent dynamics underlie versatility of T-cell receptor

7. Xingdong Guo^#, Chengsong Yan^#, Hua Li^#, Wenmao Huang^#, Xiaoshan Shi, Min Huang, Yingfang Wang, Weiling Pan, Mingjun Cai, Lunyi Li, Wei Wu, Yibing Bai, Chi Zhang, Zhijun Liu, Xinyan Wang, Xiaohui F Zhang, Chun Tang, Hongda Wang, Wanli Liu, Bo Ouyang, Catherine C Wong, Yi Cao, Chenqi Xu. Lipid-dependent conformational dynamics underlie the functional versatility of T-cell receptor. Cell Res. 2017, 27, 505-525. 文章链接

Profiling selective binding to promoter CpG islands by a single-DNA mechanical footprinting assay

8. Wenmao Huang, Jie Yan. Profiling selective binding to promoter CpG islands by a single-DNA mechanical footprinting assay. Biophys. J., 2021, 16, 3235-3236. 文章链接

Reversible hydrogels with tunable mechanical properties for optically controlling cell migration

9. X. Wu^#, Wenmao Huang^#, W.-H. Wu^#，Bin Xue, Dongfang Xiang, Ying Li, Meng Qin, Fei Sun, Wei Wang, Wen-Bin Zhang, Yi Cao. Reversible hydrogels with tunable mechanical properties for optically controlling cell migration. Nano Res., 2018, 11, 5556–5565. 文章链接

Dimerization of cell-adhesion molecules can increase their binding strength

10. Wenmao Huang, Meng Qin, Ying Li, Yi Cao, Wei Wang. Dimerization of cell-adhesion molecules can increase their binding strength. Langmuir, 2017, 6, 1398-1404. 文章链接

3. Wenmao Huang, Shimin Le, Yuze Sun, Dennis Jingxiong Lin, Mingxi Yao, Yi Shi, Jie Yan. Mechanical stabilization of a bacterial adhesion complex. J. Am. Chem. Soc., 2022, 144, 37, 16808-16818.

8. Wenmao Huang, Jie Yan. Profiling selective binding to promoter CpG islands by a single-DNA mechanical footprinting assay. Biophys. J., 2021, 16, 3235-3236.

9. X. Wu^#, Wenmao Huang^#, W.-H. Wu^#, Bin Xue, Dongfang Xiang, Ying Li, Meng Qin, Fei Sun, Wei Wang, Wen-Bin Zhang, Yi Cao. Reversible hydrogels with tunable mechanical properties for optically controlling cell migration. Nano Res., 2018, 11, 5556–5565.

10. Wenmao Huang, Meng Qin, Ying Li, Yi Cao, Wei Wang. Dimerization of cell-adhesion molecules can increase their binding strength. Langmuir, 2017, 6, 1398-1404.

书籍列表

Single-molecule Atomic Force Microscopy

1. Wenmao Huang, Yi Cao*, et al. Single-molecule Atomic Force Microscopy, 软物质前沿科学丛书, 2021 (基于原子力显微镜的单分子技术). 书籍链接

Micropipette-based single-cell mechanical quantification

2. Wenmao Huang, Jie Yan*, et al. Micropipette-based single-cell mechanical quantification. Methods Mol. Biol. Springer, 2022 (基于玻璃微管的单细胞操控技术). 书籍链接

1. Wenmao Huang, Yi Cao*, et al. Single-molecule Atomic Force Microscopy, 软物质前沿科学丛书, 2021 (基于原子力显微镜的单分子技术).

2. Wenmao Huang, Jie Yan*, et al. Micropipette-based single-cell mechanical quantification. Methods Mol. Biol. Springer, 2022 (基于玻璃微管的单细胞操控技术).